Purine nucleosides
Medchemexpress LLC 6-Thio-2'-Deoxyguanosine | 789-61-7 | 99.7% | 283.31 | 100 MG
6-Thio-2'-Deoxyguanosine is a nucleoside analogue that can be incorporated into de novo-synthesized telomeres by telomerase. It causes rapid cell death in most tested cancer cell lines and decreases tumor growth rate in mouse xenograft models, increasing telomere dysfunction in tumor cells in vivo.
- Nucleoside analogue
- Can be incorporated into de novo-synthesized telomeres by telomerase
- Induces rapid cell death in cancer cell lines
- Decreases tumor growth rate in mouse xenograft models
- Increases telomere dysfunction in tumor cells in vivo
- DNA/RNA synthesis inhibitor
eMolecules 8-Bromo-2'-deoxyadenosine | 14985-44-5 | | 1g
Combi-Blocks | 8-Bromo-2'-deoxyadenosine | 1g | 457917203 | QB-6653 | 95.000 | 14985-44-5 | | 330.142 | C10H12BrN5O3
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Cayman Chemical 2-DeoxyadenosIn-5-monphos 5g
A derivative of AMP that has been used in the synthesis of novel photoaffinity labels for incorporation into DNA and to study adenosine-based interactions during DNA synthesis and DNA damage
Medchemexpress LLC 2'-deoxyadenosine-5'-monophosphate | 653-63-4 | 99.2% | 331.22 | C10H14N5O6P | 25 MG
2'-Deoxyadenosine-5'-monophosphate (dAMP) is a deoxyribonucleotide used as an analytical standard and reference material for nucleic acid research, method validation, and chromatographic or mass-spectrometry assays. Supplied as a solid in amber glass packaging, it is intended for calibration, quantitation, and analytical method development.
- High purity analytical standard suitable for HPLC and MS.
- Purity confirmed by HPLC (99.15% reported by COA).
- Molecular formula C10H14N5O6P and molecular weight 331.22.
- Supplied in brown glass to protect from light and moisture.
- Intended for calibration, method validation, and quantitative analyses.
Medchemexpress LLC 2'-Deoxyadenosine monohydrate | 16373-93-6 | 99.9% | 269.26 | 1 ML
2'-Deoxyadenosine monohydrate is an adenine nucleoside used in research that demonstrates various biological activities including the inhibition of glucose-stimulated insulin release and islet cAMP accumulation. It also activates caspase-3, promotes apoptosis, inhibits SAHH activity, and has an anticancer effect on colon cancer by inhibiting cell growth.
- Inhibits glucose-stimulated insulin release.
- Inhibits glucose-stimulated increases in islet cyclic AMP (cAMP) accumulation.
- Activates caspase-3 and promotes apoptosis.
- Inhibits the activity of S-adenosyl-L-homocysteine hydrolase (SAHH).
- Inhibits the growth of various cells.
- Has an anticancer effect on colon cancer.
Cambridge Isotope Laboratories 8-Hydroxy-2-deoxyguanosine (15N5 98%) 25 ug/mL in water 1 2 mL
8-Hydroxy-2-deoxyguanosine (15N5 98%) 25 ug/mL in water 1 2 mL
Medchemexpress LLC Adenosine, 2-amino-2'-deoxy- | 4546-70-7 | MFCD00047240 | 99.6% | 266.26 g·mol⁻¹ | C10H14N6O3 | 5 G
2-Amino-2'-deoxyadenosine is a modified deoxyribonucleoside (CAS 4546-70-7) used as a building block in oligonucleotide synthesis and nucleic acid research. Supplied for research use only, it is offered in solid and solution formats and accompanied by analytical documentation to support quality and reproducibility.
- High purity (99.6%).
- Available in multiple sizes, including 5 g and solution formats.
- Molecular weight 266.26 g·mol⁻¹; formula C10H14N6O3.
- Certificate of analysis available for batch verification.
- Intended for research use only; not for human or veterinary use.
Medchemexpress LLC 2'-Deoxyadenosine 5'-triphosphate disodium | 74299-50-6 | 99.9% | 535.15 | 10 MG
2'-Deoxyadenosine 5'-triphosphate disodium is a nucleotide with important biological activities. It serves as a substrate for a variety of polymerases, including DNA polymerases and reverse transcriptases. This compound plays a key role in DNA synthesis and reverse transcription. It is also widely used in in vitro reactions in molecular biology research.
- Serves as a substrate for a variety of polymerases
- Plays a key role in DNA synthesis
- Plays a key role in reverse transcription
- Widely used in in vitro reactions in molecular biology research
Medchemexpress LLC 3′-Deoxyguanosine | 3608-58-0 | 97.0% | 267.25 | 5 MG
3′-Deoxyguanosine is a derivative of Guanosine. It interacts with human purine nucleoside phosphorylase through hydrogen bonding with residues like Glu201 and Asn243. This compound shows moderate displacement activity for [3H]-guanosine in rat meninges and is useful for studying the mechanism of guanosine receptors and purine metabolism.
- Derivative of Guanosine.
- Interacts with human purine nucleoside phosphorylase via hydrogen bonding.
- Exhibits moderate displacement activity for [3H]-guanosine in rat meninges.
- Useful for studying guanosine receptor mechanisms and purine metabolism.
- For research use only.
Medchemexpress LLC 2'-deoxyadenosine | 958-09-8 | MFCD00005754 | 99.9% | 251.24 | C10H13N5O3 | 25 MG
2'-deoxyadenosine is an analytical standard of the adenine nucleoside 2'-deoxyadenosine supplied for research and analytical use. It inhibits glucose-stimulated insulin release and cAMP accumulation, activates caspase-3 to promote apoptosis, and shows antiproliferative effects in some cell models. It is intended for use as a reference in HPLC, GC, and MS methods and is not for human use.
- Analytical standard for HPLC, GC, and MS applications.
- High purity, 99.9% (as supplied in COA).
- CAS number 958-09-8 for unambiguous identification.
- Molecular formula C10H13N5O3; molecular weight 251.24.
- Available in small pack sizes suitable for method development and reference standards.